There are several ways to determine the biological age of your body. By quantifying your biological age, you can determine whether your health routine is helping or hurting your health.

There are several technologies that can be used to calculate your biological age, including:

IgG Glycome: This test measures glycans3 which sit on IgG antibodies. Glycans are complex sugars necessary for cell communication. These levels change in response to lifestyle choices, disease, and aging.

IC NAD+: Nicotinamide adenine dinucleotide (NAD+) is associated with the aging process4 and differs significantly in men and women. NAD helps regulate DNA transcription, program cell death, and cell signaling. NAD declines with age. This can be measured in a blood test.

DNA methylation: It’s important to know that while the DNA in your body doesn’t change, the way that DNA is expressed is affected by environmental factors, many of which are within your control. Researchers use a clock based on DNA methylation early disease biomarkers5 and predictors of life expectancy.

Blood transcriptome and gut microbiome: The gut microbiome6 is unique to an individual and changes with age. your the blood transcriptome includes clinical biomarkers associated with biological age and gene expression7.

Some at-home biological age tests use measurements of the gut microbiome and blood transcriptome to achieve an accurate estimate.

“The biological age test uses biomarkers to estimate biological age. There are many ways to estimate biological age, for example by tracking movements or measuring clinical markers in the blood,” explains Cuellar.

However, Cuellar adds that “tests based on DNA methylation (tests for epigenetic age) are considered the gold standard.”