Research on PharmaGABA® and better sleep (plus how to get it)*
Meet PharmaGABA®, a version of the neurotransmitter GABA that is made using a fermentation process not too dissimilar to that used to make cheese, wine, and other fermented foods.
Renowned integrative medicine physician Robert Rountree, MD, has been using bioactive GABA to help clients sleep for decades with great success.*
“It’s amazing stuff,” Rountree previously told mindbodygreen co-director Jason Wachob. “It has been found to bind to the same GABA-aminobutyric acid receptors in the brain that help us calm down and relax.”*
Rountree explained that some of his medical colleagues initially doubted that manufactured GABA could have the same effect as the real deal, but recent studies have shown otherwise. In one 2018 double-blind, placebo-controlled study of 40 patients who reported difficulty falling asleep, four-week mode GABA2 have been shown to decrease sleep latency (the time it takes a person to fall asleep) and increase sleep efficiency (the percentage of time a person actually spends asleep).*
“I wouldn’t say it knocks you out,” Rountree clarifies. “It just makes you feel calmer and more relaxed, and there’s research that shows it actually affects brain waves.”*
In one of these clinical trials, EEG measurements showed that GABA, compared to water and L-theanine (another amino acid thought to promote sleep), significantly increased alpha brain waves3 (relaxant) and reduced his beta waves (stimulatory) within an hour of administration.* In short, says Rountree? “This is the real deal.”