Recently, NAD+ infusions have become quite popular. NAD+ is a coenzyme found in all cells of the body and is involved in a number of functions, including mitochondrial energy production, DNA repair, cell survival, and metabolism.

“We constantly have NAD+ in every cell of our body, going from a high-energy state to a low-energy state and facilitating expansive biochemical reactions,” explains Cook. “They can generate energy in your mitochondria by activating DNA repair, [or] activation of the sirtuin superfamily, which is relevant to longevity extension.’

Like most good things, your natural supply of NAD+ declines as you age, but maintaining NAD+ through supplements, lifestyle habits, and treatment can help you maintain stable levels. Cook is particularly interested in NAD+ IV therapy, where NAD+ is given through a vein in normal saline. Some say this is the easiest way to increase your NAD+ levels—as long as you do it under the supervision of a responsible health professional.

“Overall, I think it’s very safe,” says Cook, although it’s not for everyone. Always check with your doctor before making an appointment to make sure it’s right for you. We also suggest reading our complete guide to NAD+ IV therapy to learn more about potential benefits and side effects.